Michael Rwagasana was born in 1927 in Gitisi Nyamagana of Ruhango District in the Southern Province. He attended Groupe Scolaire Astrida attaining a Diploma
He married Suzana Nzayire in 1957 and were blessed with three children
Rwagasana attained several distinctive positions due to his integrity; he later became the Personal Secretary of King Mutara III Rudahigwa from 1954.
His unvarying advocacy for unity, independence and denouncing ethnic differences won him a job as the First Rwandan Secretary in the United Nations.
He died in prison under the regime of Gregory Kayibanda for declining to embrace ethnic segregation.